Maybe, but as someone who's done a 4-month backpacking stint, I was over it after 1 month, so I think even just that amount of time is enough to make an impact psychologically. By month 3, I was acclimated to it, but still eager to be done with it.

(As an aside, the experience actually made me less enthusiastic about nature and gave me a deeper appreciation of civilization. Never in my life did I have such deep gratitude for having a flat paved sidewalk to walk on.)