I'd love the current generation of POSs in power to die off naturally before those advancements will be applied, thank you.
People will still die, even in a world without ageing, which this treatment doesn't promise.
Without that people have lived longer are more likely to have lower risks of death per year. And thus older people in such a society would on average live longer.
> it isn't the "primary cause
Only if you’re using an inaccurate definition of aging. If everyone over 20 should have the same risk of cancer as 20 years olds the total number of cancers would drop by more than half.
If someone has an increased risk of death per year from cancer or whatever because something is failing over time they are still aging.
If the rate per year stays the same IE being 20 or 20,000 has no impact on your risks of cancer each year then someone that’s 20,000 likely takes very few other risks and is more likely to live another 20,000 years than the random 20 year old.
Then, one day, the are told their important and distant "parents" are finally arriving to bring them away to their new life...
Anyway, the point is that any aging wealthy pedicidal murderers are also gonna insist the body is perfect before they move in. The easiest way to do that without conjuring more new technology is the force the future-victim to do it.
And you also reminded me of the flawed but moving film "Never Let Me Go" from 2010 about a more present version of this. Oh, and there's also Michael Bay's "The Island".
(In practice, almost everything over 5 years away, even when already in early human trials, has this property; the only reason the Covid vaccines happened faster is that everyone was willing to throw unlimited resources at the problem and do simultaneous tests on all candidates, and in a pipeline, rather than cost-efficiently and slowly like everything else has been).
In-vitro tissue culture is already a thing (including brain organoids, if you want a brain to control a robot: https://en.wikipedia.org/wiki/Cerebral_organoid), as is 3D bio-printing.
IIRC, there's no current way to scan even a single living synapse/synaptic cleft/dendrite combination to read out the corresponding connection strengths, let alone for the whole brain, so we can't yet scan a brain — but if we could do that, writing it back to a fresh blank one currently seems(!) like the easy part, as neurons change shape and grow in response to electrical gradients.
This, er, Brain of Theseus would retain operational patterns even if the individual cells have been replaced.
A variation on that would be too do it stochastically, constantly substituting a miniscule percentage of cells evenly across the entire brain.
This thread is about stem cells in monkeys.
https://blanu.net/curious_yellow.html
https://en.wikipedia.org/wiki/Glasshouse_(novel)
h/t HN user cstross
Many of the worst people in humanity, seem(ed) to act like they thought they were immortal.
Even being grazed by a bullet didn't stop Trump praising the second amendment.
(Though I say that as a non-American, and someone for whom the 2nd was part of why I never even considered attempting to migrate to the US; I do recognise the language used to support it as a quasi-religious badge of identity, i.e. hard to shake).
This at least gives the semblance of Trump having and sticking to a set of principles (though I suspect it's more to do with what his supporters would accept)
The hate of men will pass, and dictators die, and the power they took from the people will return to the people. And so long as men die, liberty will never perish…”
And that's good because, for my part, I plan to shuffle off this mortal coil in time not to see America elect Nick Fuentes as President.
I have heard variants on this assertion:
"Two of the most prominent purported underlying causes of aging are chronic inflammation and senescent cells."
One thing that surprises me is that telomeres aren't mentioned.
I also don't understand how this is happening (is apoptosis somehow triggered?):
"Now, the Academy researchers demonstrate that SRCs reduce senescent cells, measured using a blue dye called SA-β-Gal, in multiple organs, including the brain, heart, and lungs."
The main mechanism of action appears to be:
"The therapeutic efficacy of MPCs is largely attributed to their paracrine actions, with exosomes playing a pivotal role in mediating these effects."
The researchers do not appear to fully understand how this is happening:
"Among the diverse geroprotective functions of SRCs in the brain and ovary, the restorative effect of SRC-derived exosomes on aged cells and their surroundings emerges as a key mechanism. Rejuvenation of aged cells by exosomes likely involves multiple pathways and targets."
These treatments aren't panaceas. The benefit would almost certainly accrue inversely with age.
I don't really blame humans in particular, a bear can eat it's prey alive and feel nothing at all about it, and many other similar examples of cruelty exist in nature, many even eat their own species in special circumstances, despite that I don't consider any of them evil.
Nothing short of a highly contagious virus that affects the brain and makes us more emphatic (with no other side effect) would break the cycle, but that's just sci-fi talk.
It's also not particularly challenging to see society lacks any intrinsic defence from the most ruthless and greedy from advancing in any given power structure inside of it, it's a long term damage so it's abstracted away while more immediate issues take presedence, it's in our DNA to give too priority to immediate threats, while long term problems such as this don't make the top 10 (another example being climate change, etc)
For every evil old person today, there's a handful of evil younger people behind them, just because of demographics.
Hitler ultimately died from the sheer gambler's recklessness of reaching for far too much that belonged to too many other powers, and being burned by all the consequences. Had he not started a multi-front world war against almost every single one of the world's other major nations, he could have stayed safely in power as Germany's beloved dictator right up until any old age he managed to reach (as Franco pulled off by much more wisely focusing on consolidating domestic power and avoiding wars)
Societies do have ways of dealing with tyrants, yes, and mostly it's just by rewarding them with more. The bad parts mostly happen to utterly foolish tyrants who make tremendous missteps.
150 is the new 70
There are a million problems that will arise if people won't be able to die and that's just another one of them.