I've made a point of staying away from more radically different layouts precisely because I live in a reality where use of laptop keyboards is frequent and dragging an external board around isn't really practical.

It would be nice if laptop manufacturers standardized on a modular keyboard deck design, making it viable to do small-batch group buys of replacement decks with relatively esoteric layouts. This wouldn't cover every possible layout due to size constraints but it'd be a marked improvement.