What job are we talking about and why is TypeScript or typed Python actually bad at it?
The comment about Typescript was really about JavaScript. It's a patch on top of JavaScript, which is a shit show and should have been replaced before it ended up forming the backbone of the internet.
Python, typed or otherwise, isn't good for anything past prototyping, piping a bunch of machine learning libraries together, or maybe a small project. The minute the project gets large or starts to move towards actual production software Python should be dropped.
WASM is obviously an option these days and well, but my understanding is that it's a long way from taking over.