Exact same drive? You might want to check that drive isn't silently corrupting data.
I still blame btrfs, something very similar happened to me.
I had a WD Green drive with a known flaw were it would just silently zero data on writes in some random situations. EXT4 worked fine on this drives for years (the filesystem was fine, my files had random zeroed sections). But btrfs just couldn't handle this situation and immediately got itself into an unrecoverable state, scrub and fsck just couldn't fix the issue.
In one way, I was better off. At least I now knew that drive had been silently corrupting data for years. But it destroyed my confidence in btrfs forever. Btrfs didn't actually lose any additional data for me, it was in RAID and the data was all still there, so it should have been able to recover itself.
But it simply couldn't. I had to manually use a hex editor to piece a few files back together (and restore many others from backup).
Even worse, when I talked to people on the #btrfs IRC channel, not only was nobody was surprised the btrfs had borked itself due to bad hardware, but everyone recommend that a btrfs filesystem that had been borked could never be trusted. Instead, the only way to get a trustworthy, clean, and canonical btrfs filesystem was to delete it and start from scratch (this time without the stupid faulty drive)
Basically, btrfs appears to be not fit for purpose. The entire point of such a filesystem is that it should be able to run in adverse environments (like faulty hardware) and be tolerant to errors. It should always be possible to repair such a filesystem back to a canonical state.