This last wave of work was actually triggered by the industry over the last 2 years, as the volume of biological sequence data is growing rapidly and more BioTech and Pharma companies are rushing to scale computational pipelines.

Namely, if you look at DeepMind’s AlphaFold 1 and 2, bulk volume of compute time is spent outside of PyTorch - running sequence alignment. Historically, with BLAST. More recently, in other labs, with some of my code :)