Note also that this is the intersection of bits that are available on both ARM and x86. If you want it to be portable, you need both architectures. Just because ARM64 doesn’t use a bit doesn’t mean that x86 doesn’t and vice versa.
Both x86 and ARM have proposed standards for pointer tagging in the high bits. However, those bits don’t perfectly overlap. Also, some platforms don’t fully conform to this reservation of high bits for pointer tagging, so there is a backward compatibility issue.
Across all of that, I found six high bits that were guaranteed to be safe for all current and future platforms. In practice you can probably use more but there is a portability risk.