Also after some research about rate of change: It's extremely slow.

HPV is a double-stranded DNA virus with very high replication fidelity. The emergence of types like 16 and 18 happened hundreds of thousands of years ago.

I did know it was quite slow but not just how slow. Very long term vaccine efficacy is expected.

The total prevalence of all high-risk cases went down in the study, from 46% in the pre-vaccine era to 32% post vaccine.

16/18 were chosen because they are highly carcinogenic and cause the most cancer, they are the two most aggressive high risk types. They cause 70% of all the cancer but are much less than 70% of the cases of high risk strains.

It takes real mental gymnastics to downplay how positive this vaccine is.

That study is small, observation based and controversial, and the researchers have data from a randomized follow up study that they have been keeping secret for the last 14 years. The coverage of the controversy has mostly been in Danish media, despite these hacks advising the current US administration. See https://www.sensible-med.com/p/the-false-narrative-of-nonspe... for a writeup in English.

Not my field but just looking at that I see variations as big as the signal they are supposedly detecting. Looks an awful lot like noise.

And note that it's possible for a vaccine to have a negative survival benefit yet be a good idea--in a population with herd immunity a vaccine provides little benefit to those who receive it so long as enough people receive it to provide the herd immunity. But if too many don't get it the risk from not getting it goes up considerably. Look at what has been happening with measles--measles was basically unheard of, the quacks said not to vaccinate (remember, Wakefield was attacking a specific vaccine that he stood to profit from the controversy, Worm Brain doesn't believe in infectious disease in the first place), now we have people dying of measles.

> Setting High-mortality countries in Africa and Asia.

this reads like a big grain of salt on the results.

from the paper, its more specific that girls who got the DTP vaccine and also not another vaccine afterwards have a higher mortality rate.

but also that its wildly different by location

> Other vaccines, for example DTP, have been shown to cause higher long term mortality rate

Sure. This one hasn’t.

That said, I frankly think people should be free to vaccinate as they please, and cities, states and private businesses free to include and exclude folks based on vaccination status as they please. (I’m also in favor of letting insurance companies choose if they want to cover diseases someone chose to get by going unvaccinated.)