I’d say the main sad thing is once the Bay Area was taken over by VC bros in fleece vests and mega corps it lost its soul. In some ways the place became the thing it started out fighting against, and so have many of its companies. Eg Salesforce started as the rebel solution to big bloated clunky tech, and now Salesforce is the big bloated clunky tech that a new generation groans at using.
SF turning into an almost literal dumpster fire hasn’t helped as any good “hub” also needs a clear downtown, and most folks actively avoid going into SF these days.