Yes, so far my preference has been Tirz. Though cost for Sema is significantly less.

It could also be the case that the dose on the Reta I used was too low. I've had a few people mention that they also felt it was fairly weak mg-for-mg, maybe 10mg would have been better.

There is a newer formulation, combining Sema with Cagrilintide that is probably the most effective option atm:

https://www.nejm.org/doi/full/10.1056/NEJMoa2502081

Price wise, this should give a general idea what Chinese sources sell at:

  Semaglutide 10mg/vial x 10vials $80
  Tirzepatide 10mg/vial x 10vials $72
  Retatrutide 10mg/vial x 10vials $130
  Cagrilintide 5mg + Semaglutide 5mg 10mg/vial x 10vials $170

(Note that even though Tirz is a few dollars cheaper, 2.5mg Sema = 15mg Tirz or thereabouts)