Interesting -- would love to hear anything more you have to share! The research numbers would suggest that Reta was top, results wise.
Any other significant differences you felt/noticed? Also, do you find Tirz to be an imiprovement over Sema?
Any other significant differences you felt/noticed? Also, do you find Tirz to be an imiprovement over Sema?
It could also be the case that the dose on the Reta I used was too low. I've had a few people mention that they also felt it was fairly weak mg-for-mg, maybe 10mg would have been better.
There is a newer formulation, combining Sema with Cagrilintide that is probably the most effective option atm:
https://www.nejm.org/doi/full/10.1056/NEJMoa2502081
Price wise, this should give a general idea what Chinese sources sell at:
Semaglutide 10mg/vial x 10vials $80
Tirzepatide 10mg/vial x 10vials $72
Retatrutide 10mg/vial x 10vials $130
Cagrilintide 5mg + Semaglutide 5mg 10mg/vial x 10vials $170
Reta 8mg -22% body weight at 48 weeks
CagriSema -20.4% body weight at 68 weeks
CagriSema has been on my radar for a while, and it's certainly going to be exciting.
Here's a slightly better link for the curious:
One person can easily turf as 1000 too, posting from a few accounts every day over the course of a year.
I swapped to Reta from Tirz and have found it to be a significantly better option myself.