I'm assuming this space has already been heavily optimized by the Bitcoin miners on their way to ASICs.
(ASIC simulation on an FPGA will retain the combinatorial stages but run at dramatically lower fMax)
Edit - I misread your comment. ASIC designers will use FPGAs to test their design but it won't be optimized for FPGAs which have a different logic-and-memory characteristic than ASICs. There aren't many great SHA256 FPGA implementations, largely because there's not that much demand for one
No matmul coin where the hardware could be repurposed for AI stuff?