Anything else? Because that's the only one I can think of.
I'd expect HPC would be another, since a lot of algorithms that run on those clusters are bottlenecked by latency or throughput in communication.
For the parent: and not only bottlenecked at single hops but also hampered by the propagation of latency as the hops increase, depending on the complexity of the distributed system design.
> […] by the propagation of latency as the hops increase […]
Which is why you get network topologies other than 'just' fat tree in HPC networks: