I'd say advanced users or skilled staff.
20+ years ago e.g. Athlon XP had a small CPU die in the middle and 4 round spacers in the corners for a proper heatspreader installation. Despite the CPU die wouldn't clock down and go in flames in case of cooler removal during operation.
Nowadays with a safer CPU monitoring its temperature, one has to risk to remove the heatspreader and replace it with "special" direct die cooling resulting in either a bit more performance or 15-20 grad lower temperatures or a smaller or a silent cooler. One is free to choose.
Sure, even advanced user must take more care working around the naked die. But the technology to make this safer than before could have also matured.
The latest CPUs still include such a thermal protection, which is independent of the turbo clock frequency management, which is based on the power and current limits, which can be modified by the user, e.g. for overclocking.
Older CPUs, until about the middle of the nineties, could be destroyed by inadequate cooling. This has forced both Intel and AMD to implement thermal protections, to avoid requests for CPU replacements.
I have no confirmation for the following but I've considered that the pre-installed and hard and risky to remove the pretty massive heatspreader plate works not only as die physical protection but also as a minimal needed buffer for heat dissipation in case of rapid cooler removal.
[1] "What happens when the CPU cooler is removed?" (Tom's Hardware Guide, 2001)
https://www.youtube.com/watch?v=y39D4529FM4
https://www.youtube.com/watch?v=UoXRHexGIok
P.S. Another rather philosophical question I have since a ventilator (not just some heatspreader) was required for the first time for CPU to operate as advertised. Can one consider that CPUs are actually factory overclocked since then? Even though not to the absolute limit, e.g. Celeron 333A (@66) up to 500 (@100) manually.