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Why do people insist on complicating all this so much ... just take a hit of whatever and experience it for yourself.

I believe people complicate it because brain chemistry modification is mostly a one way change.

There’s plenty of reasons but that’s not a great reason for or against - there is no process you can do to your brain that isn’t a one way change.

There is always a lesser change, which may be what you want. Nobody wants brain damage.