Even if you hold that you need that genetic predisposition, and that a perfectly sane person can never become "insane" as a result of an experience (not a position I agree with), there is still the very real possibility that many people with the predisposition would never have had this "already insane" condition ever triggered or exposed. Think about the suicide cults that have formed, notably Jonestown. It's easy to consider the mass suicide (and murder of the members' own children) as "insane" behavior. What are the odds that every single person was genetically insane? Comparatively, what are the odds that an extremely persuasive and charismatic personality can rewire a person's reasoning to believe something "insane"?
If you think of ChatGPT as capable of being an automated Jim Jones, I think the danger becomes more clear. These tools are not incapable of being dangerous.