One theory (which CERN is using) is to argue that almost all matter was destroyed, and that the current observable universe is merely the tiny leftover due to slight differences in behavior, making the Big Bang look more like the Ludicrous Bang. This, of course, just contributes to religious snickering at how all problems are solved by adding another billion years to the timeline, over and over.
https://home.cern/science/physics/matter-antimatter-asymmetr...
Edit to reply: They behave differently; but why there is more of one than the other, remains unexplained; as regardless of how they behave, both should have been initially created in equal numbers. As for Sabine Hossenfelder's quote, that's a religious-faith level cop-out. When science requires faith, should it not be treated as a religion?