So we have:
CISC – which is still used outside the x86 bubble;
RISC – which is widely used;
Hybrid RISC/CISC designs – x86 excluding, that would be the IBM z/Architecture (i.e. mainframes);
EPIC/VLIW – which has been largely unsuccessful outside DSP's and a few niches.
They all deal with registers, movements and testing the conditions, though, and one can't say that an ISA 123 that effectively does the same thing as an ISA 456 is older or newer. SIMD instructions have been the latest addition, and they also follow the same well known mental and compute models.Radically different designs, such as Intel APX 432, Smalltalk, Java CPU's, have not received any meaningful acceptance, and it seems that the idea of a CPU architecture that is tied to a higher level compute model has been eschewed in perpetuity. Java CPU's were the last massively hyped up attempt to change it, and that was 30 years ago.
What other viable alternatives outside the von Neumann architecture are available to us? I am not sure.