Scrolling comments, I see somone else nentions this as well. I feel like this is something that got stuck in academia hell but in practice could be solved in more oractical ways. I remember various papers on fresh naming and name calculi from the 00's but why? We have a parser and we have numbers.
The reason I bring this up is because I recall it being easy to introduce bugs into de Bruijn calculi and also adding symbolic debugging to real-world languages was annoying for reasons I have no memory of.
* Note I said name not variable. (\ x . x (\x . x)) Would be (\ x#0 . x#0 (\x#1 . x#1)) similar to de Bruijn indices but could differ in other situations.