I wonder if Riot Games will ever make their games run natively on Linux? AFAIK some of their games ran via wine but they introduced an anti-cheat system that now prevents that from working.
My pipe dream is that Proton becomes so successful that it kills itself by making linux gaming profitable enough to be first party supported. My long wish of having a decent gaming and development environment will finally come true, just in time for me to not care so much about one or the other.