Intelligence is a unique spark within a cold and presumably dead universe. We should be trying to awaken the universe itself.
We should be trying to extend human lifespans within the parameters of sustainability. We should be trying to extend our species beyond death and mortality and this single planet.
If we master physics, we should reverse the light cone and bring back everyone who has ever lived [1].
We should turn every atom in the universe into us.
And then we can try to prevent the death of the universe. Or build a new one. Or several.
[1] "Down to what level?", you ask. "Beloved pets that died?" I should think even the ants. Bacteria. If we're gods, then why not?