This isn't about science, issues, or voting. The message is: "We don't like you and it would be better if you weren't around".
Also, why is NSF fielding 40,000 proposals per year? That is 110 proposals per day. Is there really that much science to perform and not enough universities to host it? Not at all. It exists because every state and local government and educational institution is incentivized to solicit federal aid. Even if a school is located in Beverly Hills, federal aid will be solicited at all levels in K-12 and higher education. Republicans are saying they don't want anything to do with that level of centralized government.