As someone who recently set up something similar in Emacs with eglot I had to ditch Python-LSP-server.

It was so incredibly slow to respond, even on a M2 Max MBP, that it lowered my productivity by orders of magnitudes (and made Emacs laggy).

Maybe I did something wrong? I don’t know.

What I do know is that I tried pyright instead as a different LSP-server for Python and I haven’t looked back.

It’s a night and day difference. It’s snappy and everything works as expected, with venvs and mypy too.