Some third-party tools exist to tweak how ClearType works, like MacType[1] or Better ClearType Tuner[2]. Unfortunately, these tools don't work in Chrome/electron, which seems to implement its own font rendering. Reading this, I guess that's through FreeType.
I hope that as new panel technologies start becoming more prevalent, that somebody takes the initiative to help define a standard for communicating subpixel layouts from displays to the graphics layer, which text (or graphics) rendering engines can then make use of to improve type hinting. I do see some efforts in that area from Blur Busters[3] (the UFO Test guy), but still not much recognition from vendors.
Note I'm still learning about this topic, so please let me know if I'm mistaken about any points here.
[1] https://github.com/snowie2000/mactype