In two weeks of using it, I got annoyed by the following: - no automatic dark-mode (against fingerprinting, some websites don't have a setting to switch it on - not sure if you can turn it off) - timezone is always UTC (can be worked-around with an extension, messed up my time tracking app and some log viewer) - login on some websites/tools is broken altogether by the strict privacy settings (did not even bother to debug, I switched to Firefox) - WebGL off by default (you can turn it on via config flag)
I switched from Firefox to Chrome and back and never had to debug and work-around so many issues. It's a decent browser, but I'm not sure the value it brings justifies the costs of time spent debugging and the inconveniences.
I will continue to use it for work, but I will not switch entirely from Firefox because I want my history available across devices.