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Comment by qwerty456127 | Hacker News Reader

> Excess B12 is really bad. Neuropathy.

How much really is dangerously excess? How do methylcobalamin vs cyanocobalamin compare in this regard? I noticed B12 supplements usually exceed the RDA by some orders of magnitude.

> Increasingly hard to get Mg tablets without Vitamin B

Same problem with iron supplements. Not particularly easy to find iron without folic acid. Folic acid can be very harmful for people with methylation problems (an extremely widespread genetic thing) who should supplement methylfolate instead. Whoever feels stimulated and harder to sleep after taking a folic acid pill - beware.

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B12 is water soluble and does not cause neuropathy. It was a error by the original poster.

As for methyl vs cyano, it depends whether you have the genetic factors that would benefit or not from methyl groups. In my case I wouldn't benefit so I don't take the methyl form and instead take the hydroxy and adeno forms.

Cyano is useless. Needs multiple steps in the liver to convert.

There’s a fair number of brands selling mg alone and fe alone. Maybe it’s hard outside the US? Or maybe places like target and CVS don’t carry them - those places do have limited options.

Yeah, I don't think I've ever seen Mg supplements with other stuff added. I'm currently using glycinate and taurate in powder form, and there's nothing else listed.

I sprained something in my lower back badly enough about a year ago that it took four trips to the chiropractor before I could get out of bed in the morning without lots of swearing. After that, it would seem to be getting better for a few days, then regress into spasms again. After a month or so of that, I remembered that Mg is supposed to be good for tendons and ligaments. I took a good dose of Mg that night, and it was significantly better the next day, and improved from there. That's the only time in my life that I've had a clear, major difference from taking a supplement.

CVS’ own brand has Mg only

https://www.cvs.com/shop/cvs-health-magnesium-glycinate-200m...

You can walk into target, Walmart, CVS, etc and have plenty of options for iron alone (which isn't widely packed with other vitamins outside a multi) and magnesium alone.

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