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... and report the bug to the app's developer! Be sure to include the sample.

If the entire system has ground to a halt such that it's difficult to actually get to Activity Monitor to do the sample, then it's likely to be a memory problem. If it's just one app, it's probably something else.

If the system is hung such that you can't get Activity Monitor to sample, use command-option-control-shift-period to run sysdiagnose. Attach the resulting /var/tmp/sysdiagnose_$(TIME).tar.gz to your bug report.

And inside that tar.gz file is a spindump.txt file, which will have the samples of whatever application is spinning at the moment, just like if you used Activity Monitor to sample it.

I had never heard about it... Wonderful.

good idea - upvoted! :)