This is the press release that is being republished with ads in the post link https://med.stanford.edu/news/all-news/2025/03/ozempic-rival...
This seems to be the paper, but its behind a paywall.
Anyone with access can tell me if they publish the 12mer amino acid sequence? Is there more to it (post translational modifications)
Or is it just the peptide?
Yes, the paper provides the 12-mer amino acid sequence of BRP: THRILRRLFNLC .
Regarding post-translational modifications, the BRP peptide was synthesized with a C-terminal amidation, which was critical for its bioactivity. The non-amidated version of BRP was inactive in vitro . Additionally, the paper mentions that the C-terminal cysteine (C12) was synthesized as a free thiol .
So, BRP is not just a simple peptide—it has a key post-translational modification (C-terminal amidation) that influences its function.