I once took Ketamine, "fell through the bed" and spent half an hour in a different dimension, peacefully floating above and close to incredibly detailed, dull and dark colored patterns while unable to form language-based thoughts until I suddenly snapped out of it. The music I was listening to (HUSBANDS (Run Along, Son, etc.)) helped a lot and was just incredible, though I am still not sure if I could have had the same great experience with different music.

It was THE single most amazing and out-of-this-world thing I ever experienced and I highly recommend it to everyone.

I don't know if it helped me in any way with my depression though. No hangover. No lasting changes.