The used to exist (e.g. Hyves, StudiVZ), but they are murdered by FAANG. However, there are still locally successful companies that could expand to the rest of Europe if US companies were dropped. E.g. just speaking of The Netherlands, Bol.com is much more popular than Amazon, Marktplaats is more popular than eBay (which is pretty much non-existent here) and owned by a Nordic company, etc., iDEAL is much more popular for payments than PayPal, Stripe, etc. (and works far better). Such companies can fill the void.
Microsoft will be tough to replace. There are good alternatives, but retraining personnel, etc. will take years. Google, I am not sure. Their cloud services are replaceable. Search may be tougher, but the quality of Google Search has become so bad that it's often easier to ask an LLM.