Ed: among the ways millions of lives could be lost: losing control of our nuclear arsenal or nuclear materials due to haphazardly firing people responsible for maintaining them. Bungling the response to the next pandemic, due to haphazardly firing people, cutting science funding and deleting inconvenient data. Starvation and disease from ceasing aid around the world. There's also the wars likely to result from the collapse of trust in the US as a security partner, but I suppose it's not correct to blame that on DOGE per se, even if it's an extension of the same principle.