That's my main use case not-yet-supported by uv. It should not be too difficult to add a feature or wrapper to uv so that it works like pew/virtualenvwrapper.

E.g. calling that wrapper uvv, something like

  1. uvv new <venv-name> --python=... ...# venvs stored in a central location 
  2. uvv workon <venv-name> # now you are in the virtualenv
  3. deactive # now you get out of the virtualenv

You could imagine additional features such as keeping a log of the installed packages inside the venv so that you could revert to arbitrary state, etc. as goodies given how much faster uv is.