> Off-Topic: Most stories about politics, or crime, or sports, or celebrities, unless they're evidence of some interesting new phenomenon. Videos of pratfalls or disasters, or cute animal pictures. If they'd cover it on TV news, it's probably off-topic
The lay-offs are apparently not just affecting health agencies but are across the entire range of US government agencies, and are extensive. This will affect a great many people, and I feel very sad for their predicament - but it will also affect the regulatory, economic, and public policy environment in the US, as well as US government funded technology and research. Many people who use this site will be affected, directly or indirectly. As will many of the companies that they work for.
So, apart from the awful human cost, I believe the article is HN-relevant.
If you're upset that tech and politics have merged, blame Musk.
...If it's about the trump administration.. what is it supposed to start with?