I put a lot of effort into the layout and style of my resume, and wrote it in TeX. My knee-jerk response when people won't glance at my .pdf resume is that they are lazy, don't respect the effort that goes into design and layout, and only wish to keyword search.
This may not be true of your case, just saying what my emotional response is in that situation. I agree that minor hurdles to weed out the insincere are valuable.