Have done both clinical Ketamine and Psilocybin therapy.
Ketamine was very interesting. Proper completely dissociative "K-hole" experience. I feel like it helped with Anxiety, but I can't pinpoint "why" from an introspective perspective.
Psilocybin on the other hand. Was a hero dose, and I'm a changed person afterwards.
Could feel the "layers" of my identity being stripped off, almost regression to a more child-like state. Very interesting experience. Had strong synesthesia: sounds would produce colors, colors would produce tastes, fun experience.
Near the peak of the experience I had these strong recurring auditory hallucination of my mothers says all these random words from my youth, these were accompanied by strong feeling of anxiety. After a lot of post-experience integration and reflection I realized that my mothers anxiety about the world was effectively "programmed" into my brain during my upbringing. e.g. Generationally transmitted anxiety.
Therapy always talks about childhood trauma, etc, but actually experiencing it was another level, and really helped me on my journey to being a less anxious person.
Before the Psilocybin experience, I suffered from existential depression: what's the point of living if the sun is going to explode in ~x billion years. Towards the peak of the experience everything was super chaotic, I felt like I was being transported into different realities (e.g. realities with different laws of physics, or different space time geometries). This was hugely anxiety inducing and would otherwise be called a "bad trip." I felt "lost" in this sea of all different realities.
As I was coming down from the peak and started to reintegrate, I had a strong distinct sense of "coming back" to our current reality. It felt like finding a safe tropical island in a sea of chaos: e.g. our currently reality is a safe space and point of stability in a sea of chaos and uninviting realities.
I was truly, deeply, grateful to be able to return to the familiar and it made me really really deeply appreciate myself and the blessing that our reality is to us.
Post the experience I also acquired the ability to observe my emotions from a third person perspective. e.g. rather than feeling "angry" I could tag the emotion "angry" and react accordingly, almost as if I gained ring 0 access to my brain when I previously only have ring 1 access.
All-in-all probably the most profound and healing experience of my life.
1. Deeply felt and understood my anxiety was generationally passed on from my mother's anxiety,
2. Eliminated my existential depression, giving me a deep appreciation for the beauty of our reality,
3. Gave me ring 0 access to my emotions making me a much more stable, calm person.