I suppose that's true normally, but I was pleased to read that you can probably reverse it if you make radical enough changes:
https://www.health.harvard.edu/heart-health/ask_the_doctor_i...
https://www.health.harvard.edu/heart-health/ask_the_doctor_i...
My understanding is that we don't have contemporary evidence of people successfully reverting arterial plaque, but I admit the studies probably didn't faithfully reproduce these starvation conditions!
https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.120.0...