This is going to be a crazy four years, if it’s only four.
For the average for-profit company, the actual business the company does has no value beyond its ability to generate profits. The damage a disruption causes today can always be offset with higher expected profits in the future.
But for many government departments, the day-to-day business is the entire point. Any disruption can easily cause irrevocable damage. Even when the net outcome is positive, the gains often cannot offset the damage, because they go to different people.
1) state's rights
2) anti-science
3) a number of people in the administration (very possibly including Trump himself) thinking that the CDC is an example of "the deep state" that conspired to keep him from winning in 2020
But, hey, Joe made groceries more expensive and the administration didn't kiss enough rear on the left side of the Dems to get Kamala elected, so, here we are.
A less nuanced answer is the HHS/CDC made Trump look bad in handling the COVID-19 pandemic and so they’re now ordered to say nothing about anything ever again.
[1]: https://static.project2025.org/2025_MandateForLeadership_FUL...
Fight the ideologues, them and their expertise are the problems.