I'm a freelance webdev with 15 years of experience, and recently I've made some new projects with Symfony Stimulus & Turbo to great success.

A few thoughts:

I tried just htmx too, too limiting. Stimulus/Turbo combination is much better.

Use the right tool for the job. Highly interactive app, like an editor? Use react or similar js framework. Mostly page/document website? A backend framework is much faster and easier to develop, and much simpler to test.

Use what you know yada yada.