> Low doses of fructose are ~90% cleared by the intestine, with only trace fructose but extensive fructose-derived glucose, lactate, and glycerate found in the portal blood. High doses of fructose (≥1 g/kg) overwhelm intestinal fructose absorption and clearance, resulting in fructose reaching both the liver and colonic microbiota.

> In many microbes, fructose is phosphorylated on its 6-position and thereby follows nearly the same metabolic pathway as glucose. In mammals, however, fructose phosphorylation occurs on the 1-position, not 6-position, catalyzed by the enzyme ketohexokinase (Khk) (Heinz et al., 1968). The location of this initial phosphorylation is a pivotal difference, as fructose 1-phosphate (F1P) can be directly cleaved into three-carbon units, whereas F6P must be phosphorylated on its 1-position by phosphofructokinase, the most heavily regulated enzyme of glycolysis, before such cleavage. Thus, fructose bypasses the gating step of glycolysis.

https://pmc.ncbi.nlm.nih.gov/articles/PMC6032988/

"try to find an actual proper double blind academic study that demonstrates a taste difference between sucrose and high fructose corn syrup"

are you not able to tell the difference between regular coke and mexican coke?