one of the best decisions I made as CTO was to focus purely on IOS devices. That massive moving target of android devices is a nightmare to develop for if you're going for bug free turkey operation. Second was moving to hire someone with "olympic ice skater" level experience with ios development. We tell our customers what devices to get and in B2b, its a very small part of their overall budget.
The second best decision was to build our server infrastructure on top of elixir/phoenix. I don't think I could have gotten this far if we used node (and I had 10 years of nodejs experience)