I think there's like a couple of major areas where it concerns me I guess. The first is when we use these types of technologies to fool people, especially (recently) politically.
The other is when we are talking about photography as art.
For someone's home photos, I really don't much mind. Do as you please I guess, if you want to remember the time and place differently than it was, so be it lol.
But it's really wild that in some cases we have art that starts as a photograph and then becomes something else entirely after editing. It takes all the patience, planning, understanding and in my opinion gratification out of it when you can just say "yea, replace the sky with this fake one so my picture looks incredibly unrealistic"
Those are the two that tend to cause me the most head shaking lately I guess.