Every job I've applied to has involved me researching the company, deciding whether I understood it, was right for the role, and wanted to work for them, and then tailoring my resume and cover letter to what that role needed. In my life, I've maybe sent 25 applications, gotten 6-7 interviews, and been hired 4 times. Pretty good batting average, and I'm not by any means especially qualified or accomplished. For me, automated spam has not been the answer, laser targeting has been.