I'm running my local development environment off of my MacBook Pro.
It consists of:
* Built in Apache/PHP, both configured how I like it
* MySQL installed via the DMG download from mysql.com
* Postgres installed via DMG download
* Redis, MongoDB, Node installed via Homebrew
* Git installed via Homebrew
* Ruby 1.8.7, 1.9.2, 1.9.3 installed and managed by RVM
* Rails and other gems installed and managed by RubyGems
* IE7, IE8, IE9 virtual machines installed via https://github.com/xdissent/ievms/