Eugenics and vitamin C as a cure all.
https://scarc.library.oregonstate.edu/coll/pauling/blood/nar...
Not a fun thing to discuss, but apparently a significant issue, which I guess should be unsurprising given some of the laws allowing underage marriage if the family signs off.
Mentioning only to draw attention to the fact that theoretical policy is often undeniable in a vacuum, but runs aground when faced with real world conditions.
The goal wasn't to mark people for ostracism but to make it easier for people carrying these genes to find mates that won't result in suffering for their offspring.