Not yet but there's a precedent for incredibly perverse incentives caused by sports gambling -- most iconically the White Sox throwing the world series in 1919.

https://en.m.wikipedia.org/wiki/Black_Sox_Scandal

Not in American college football, but in German pro soccer, someone shorted the stock of a team and subsequently tried to blow up the team with multiple bombs: https://en.m.wikipedia.org/wiki/Borussia_Dortmund_team_bus_b...

not yet, i am predicting it will happen