Not yet but there's a precedent for incredibly perverse incentives caused by sports gambling -- most iconically the White Sox throwing the world series in 1919.

https://en.m.wikipedia.org/wiki/Black_Sox_Scandal

Not in American college football, but in German pro soccer, someone shorted the stock of a team and subsequently tried to blow up the team with multiple bombs: https://en.m.wikipedia.org/wiki/Borussia_Dortmund_team_bus_b...

not yet, i am predicting it will happen

it would probably make the most sense to threaten them to throw the game vs. the spread

or pay them

that will happen for sure, if it already hasn't