I remember leaving the room, looking out a window and thinking "This guy isn't as big a prick as _that_." (I had seen something like this before.) And I went back in and said, "what are we going to do about this?" I had enough standing among this larger circle to help slow down the rumors and witch-hunting until things got sorted out, which happened quickly after Friend of GirlFriend admitted it was just a lousy story. (He was never accused of this again, and never had been before.)
We ended up living together for years, and I helped him move to university for his masters. It turned out that we had similar interests and enjoyed similar arguments and enjoyed picking stuff up off one another. He introduced me to all sorts of music, and, a Jew, learned from me to give up ice cream for Lent. (I got more from this friendship than he did.) When a friend's boyfriend moved into town for her, we took him as a roommate, and cut her out when she dumped him two weeks later -- we hardly knew the guy, but she had friends in town, and he didn't. There was the day he yelled at me for suggesting something _he_ did all the time, because it wasn't something _I_ believed in.
Unfortunately, he was killed in a freak car accident, returning from completion of his masters'. That was a long time ago. I've never come close to anything like him.
In your twenties you live with more drama. You're figuring yourself out, you do stupid things, people do stupid things to you. It's easier to see who and what people are, and you need people more to bring you through all the noise. As we age as we figure out our basic choices and move on from there. The drama recedes and the volume goes down. We get more complicated and it becomes harder to read us. Confessions that made sense as we were figuring stuff out start to seem a lot more demonstrative and overwrought. Let's face it, many of us make soul-deadening choices and become much less interesting.
As we "grow up" the stuff that was questioning and exciting starts looking like instability. The raw threads of personality that can be woven into another person get woven up into others and ourselves and tucked out of sight. For lots of people this is actually good, there is less chaos and more enjoyment and more creativity. But it does become harder to make friends.
tldr; Cherish your friends. You can lose them, and they're very hard to replace.