I've been using a Coolscan 8000 and a 2007 iMac for 17 years (prior to that, I used a Mac Mini for a short while) and only last year had to replace the scanner motherboard after an international move. To continue to use Nikon's software, the iMac is still on 10.6 Snow Leopard.

I shoot 35mm and medium format and the Coolscan pulls extraordinary detail from the negatives - vastly better than the best flatbed scanners I've ever used.