Look at the fastest linting/build tools/runtimes for JavaScript. They are mostly not written in JavaScript, because JavaScript is slow and no amount of hotspot profiling/optimization will fix that. This is also why Python's core data types for dictionaries and so on are not implemented in Python.

You can also look at any microbenchmark between pure Python and a native language of your choice, even one that uses GC like OCaml or Go, and unless the Python code has been written so that it spends all its time calling C code the way you sometimes can with regex-heavy code, Python will generally lose by a varying margin. These micro inefficiencies multiply at every level hundreds of times over to create needlessly slow, inefficient applications.

The truth is I can link benchmarks, case studies of app rewrites from Ruby to Go or something comparable, measurements about the results of using NIFs in Erlang/Elixir, etc. all day long but you'll ignore all of them.