It is not so much the wasted space that bugs me as all the metadata and processing of that metadata.
For instance, the 70,000 files in your node_modules do not need separate owner and group fields (they all belong to the same user under normal conditions) and are all +rw for the files and +rwx for the directories. If you have access to one you have access to all and if your OS is access checking each file you are paying in terms of battery life, time, etc.
On Windows it is the same story except the access control system is much more complex and is slower. (I hope that Linux is not wasting a lot of time processing the POSIX ACLs you aren’t using!)